Abstract

Autoimmune pancreatitis (AIP) has gained significant attention in recent years, with a notable increase in diagnoses due to the diagnostic utility of immunoglobulin G4 (IgG4). Despite the well-known IgG4-related type 1 AIP, a less recognized subtype known as type 2 AIP exists, which is distinct from type 1 AIP and not associated with IgG4. Type 2 AIP presents similar clinical symptoms and imaging findings as type 1 AIP, making its diagnosis challenging without specific serum markers. Tissue confirmation of neutrophilic injury to the pancreatic ducts, known as a granulocytic epithelial lesion, is crucial for diagnosing type 2 AIP. Some cases of type 2 AIP are linked to inflammatory bowel disease, particularly ulcerative colitis, but the exact relationship between the two conditions remains unclear. Questions remain regarding the pathophysiology of type 2 AIP, the possibility of similar granulocytic injuries in other organs, and the characteristics of pediatric cases. In this case report we present a concomitant autoimmune pancreatitis type 2 and colitis ulcerosa in a 10 years-old girl. The patients follow-up showed amelioration of the clinical symptoms due to the present medication.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.