Abstract

Allorecognition can be considered in many ways as recognition of complexes of (allo) MHC and (allo) peptide. The question remains as to whether the T-cell response against these complexes of MHC and peptide expressed on the cell surface of an allograft displays a diverse character on the basis of T-cell receptor diversity or whether there is indeed selection at the level of the T-cell receptor by antigen-specific T cells.

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