Abstract

The first synthesis of 6,5,5,5-tetracyclic moiety related with promising anti-HIV activity in rubriflordilactone B has been efficiently achieved. Our strategy started from cheap materials, and features the utilization of radical 1,5-H abstraction/cyclization and vinylogous Mukaiyama aldol reaction, which successfully established the array of five continuous stereogenic carbon centers in the target.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call