Abstract
A surprisingly large fraction of the eukaryotic genome is repetitive. More than one third of the human genome consists of interspersed repetitive DNA, and tandemly repeated DNA sequences may occupy as much as 10% of the human genome. The majority of the repetitive sequences are nongenic; the rest encode multigene families. The genomic organization of repetitive DNA sequences takes different forms: these repetitive sequences either disperse throughout the genome, as with short interspersed sequences (SINEs), long interspersed sequences (LINEs), and transposable elements, or, like tRNA genes and human histone genes, they may cluster in one or a few chromosomal regions.
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