Abstract
In the event of an outbreak of a high risk pathogen, such as hemorrhagic fever or smallpox, it is essential to start treating the patients and controlling infection immediately. It is a real possibility that these most dangerous pathogens be brought into Japan via well developed transportation system or terrorist attacks using biological agents, and they can be dealt with only by special BSL-4 (Bio-Safety Level 4) laboratories that satisfy BSL-4 specified by the WHO (1) . As there are no BSL-4 laboratories in operation in Japan as of 2012, it is an immediate requirement to develop a suitable environment for the operation of laboratories of this kind, in order to maintain effective health risk management for the Japanese people. In this research, we will discuss the necessary conditions for BSL-4 laboratories' operation in Japan.
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