Abstract
The cryopreservation of ovarian tissue with subsequent transplantation of the tissue represents an established method of fertility protection for female patients who have to undergo gonadotoxic therapy. The procedure can be performed at any point in the cycle and thus generally does not lead to any delay in oncological therapy. With the aid of this procedure, more than 130 births to date worldwide have been able to be recorded. The birth rate is currently approximately 30% and it can be assumed that this will increase through the further optimisation of the cryopreservation and surgical technique. The concept paper presented here is intended to provide guidance for managing cryopreservation and transplantation of ovarian tissue to German-speaking reproductive medicine centres.
Highlights
Based on advancements in systemic drug and locoregional therapy, the survival rate in malignant and non-malignant diseases has significantly improved
The cryopreservation of ovarian tissue with subsequent transplantation of the tissue represents an established method of fertility protection for female patients who have to undergo gonadotoxic therapy
The cryopreservation of ovarian tissue with subsequent transplantation is a method of fertility preservation which can be performed very shortly before cytotoxic therapy
Summary
Based on advancements in systemic drug (chemotherapy, targeted therapy) and locoregional therapy (surgery, radiation therapy), the survival rate in malignant and non-malignant diseases has significantly improved. The cryopreservation of ovarian tissue with subsequent transplantation is a method of fertility preservation which can be performed very shortly before cytotoxic therapy.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
