Abstract
AbstractThe taxane content of the needles of 57 cultivars obtained from five major nurseries in the United States is presented. The analysis of taxol (1), and five other related taxanes, 10‐desacetyl‐7‐epi‐taxol (2), cephalomannine (3), 10‐desacetyl taxol (4), baccatin III (5) and 10‐desacetyl baccatin III (6) was carried out using a high performance liquid chromatographic method developed in our laboratory. The results of these analyses showed that the total “useful” taxanes varied between 0.0232%‐0.113%, with 1 and 6 being the most abundant taxanes. The survey identified 11 cultivars with a content of 1 ranging from 0.028% to 0.062%, and ten cultivars with a content of 6 ranging from 0.028% to 0.066%; 3 and 4 each represented approximately 30%‐50% of the concentration of taxol in most cultivars. Therefore, the needles of ornamental Taxus represent a significant, rich and renewable source for taxol and other related taxanes.
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