Abstract
Three prostaglandins, PGE 2, PGF 2/ga and PGI 2 (measured as 6-keto-PGF 1α), serologically activte 6-sulphidopeptide-containing leukotrienes and hydroxyeicosatetraenoic acids were determined by radio immunoassay of mixed saliva obtained at several flow rates from 8 healthy volunteers. Flow rates ranged from 0.26 ± 0.02 ml/min when saliva production was unstimulated to 1.18 ± 0.14 ml/min (values mean ± SEM) when maximally stimulated. Concentrations of all compounds tested remained independent of changes in mixed-saliva flow rate.
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