Abstract
In the period of long development, the human body adapted to specific concentrations of trace elements. Any changes in the trace element content manifesting in a deficiency or excess of metals in the human body may impair the functioning of the skeletal and articular system and of the organs, and may also predispose the body to the development of diseases, i.e., osteoporosis. Our study aimed to analyze the concentrations of calcium (Ca), magnesium (Mg), fluorides (F-), and lead (Pb) in the infrapatellar fat pad (Hoffa’s fat pad) of subjects who had undergone a total knee replacement (TKR) surgery. We also endeavored to establish how concentration levels of those elements are affected by selected biological and environmental factors. The studied group comprised 48 residents of Western Pomerania Province: 34 women (n = 34) aged 56–87 and 12 men (n = 12) aged 59–85. Concentration levels of Ca, Mg, and Pb were established using inductively coupled plasma-atomic emission spectrometry (ICP-AES). A Thermo Orion ion-selective electrode was applied for measuring F- concentration. Subjects aged 75–87 showed higher Mg concentration values than those aged 56–74. Big city residents and smokers were found to have higher infrapatellar fat pad Mg concentration than their non-smoking counterparts and small town dwellers. Of all the elements whose concentrations we analyzed in our studies, only magnesium was found to correlate with smoking, place of residence, and age. Our findings regarding the quantities of selected elements in the infrapatellar fat pad may be used for the interpretation and analysis of biological, morphological, and mechanical changes in the human body.
Highlights
The infrapatellar fat pad or the Hoffa’s fat pad
Little research has been dedicated to the analysis of the mineral composition of the infrapatellar fat pad, in particular, the correlation between the concentrations of particular elements in periarticular structures in patients afflicted with osteoarthritis of the knee [13]
Our study has shown that the mean concentration of this element in the infrapatellar fat pad is lower than in the bone tissue, and amounts to 0.51 mg·kg−1 dm
Summary
HFB) is a component of the knee joint It is located between the fibrous membrane of the joint capsule formed. The fluoride ion (F-) plays a significant biological role in the human body, participating in the binding of magnesium, calcium, phosphorus, and in the mineralization of hard tissue. Little research has been dedicated to the analysis of the mineral composition of the infrapatellar fat pad, in particular, the correlation between the concentrations of particular elements in periarticular structures in patients afflicted with osteoarthritis of the knee [13]. The study incorporated an analysis of the influence of selected environmental factors, such as the place of residence, smoking, and nutritional status, expressed in terms of BMI (Body Mass Index) on the concentration of some elements in the infrapatellar fat pad
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International journal of environmental research and public health
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
