Abstract
While major advances have been made in the control of cooling and antisolvent crystallizations, very little progress has been made for the much more challenging pH-shift reactive crystallizations that are also quite common in industry. This paper extends the concentration control strategy developed for cooling and antisolvent crystallization to pH-shift reactive crystallization of L-glutamic acid. The straightforward extension to semi-batch pH-shift reactive crystallization is not applicable, which motivates a variant that incorporates data-based models so as to better cope with process nonlinearity. Further analysis motivates the development of control strategies that directly incorporate measurements of the key product quality attributes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
