Abstract

In step with the increased use of platelet concentrates, the lack of objective and reproducible methods to assess platelet viability in unopened packs has become more apparent. The paper describes a computerised method for monitoring changes in light transmission through platelet packs under continuous rotation and for the entire storage period. The method was tested on 24 platelet concentrates, which were monitored for varying periods of time. In all concentrates tested a distinct time could be defined where a phase with gradually increased light transmission through the concentrates started. Furthermore, 35 platelet concentrates stored in Pl-146 plastic packs were examined and divided into two groups and observed for three and four days, respectively. These concentrates were monitored continuously and subsequently compared with parameters believed to reflect the quality of platelet concentrates. Concentrates in both groups showing an early increase in light transmission were found to have lower pH values at the end of the observation periods.

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