Abstract

Brain tumor is a deadly neurological disease caused by an abnormal and uncontrollable growth of cells inside the brain or skull. The mortality ratio of patients suffering from this disease is growing gradually. Analysing Magnetic Resonance Images (MRIs) manually is inadequate for efficient and accurate brain tumor diagnosis. An early diagnosis of the disease can activate a timely treatment consequently elevating the survival ratio of the patients. Modern brain imaging methodologies have augmented the detection ratio of brain tumor. In the past few years, a lot of research has been carried out for computer-aided diagnosis of human brain tumor to achieve 100% diagnosis accuracy. The focus of this research is on early diagnosis of brain tumor via Convolution Neural Network (CNN) to enhance state-of-the-art diagnosis accuracy. The proposed CNN is trained on a benchmark dataset, BR35H, containing brain tumor MRIs. The performance and sustainability of the model is evaluated on six different datasets, i.e., BMI-I, BTI, BMI-II, BTS, BMI-III, and BD-BT. To improve the performance of the model and to make it sustainable for totally unseen data, different geometric data augmentation techniques, along with statistical standardization, are employed. The proposed CNN-based CAD system for brain tumor diagnosis performs better than other systems by achieving an average accuracy of around 98.8% and a specificity of around 0.99. It also reveals 100% correct diagnosis for two brain MRI datasets, i.e., BTS and BD-BT. The performance of the proposed system is also compared with the other existing systems, and the analysis reveals that the proposed system outperforms all of them.

Highlights

  • The brain is considered one of the most important organs, being responsible for memory, emotions, vision, motor skills, reactions, respiration, and a lot of other regulating functions of the human body

  • As the brain is filled with the blood-brain barrier (BBB), so the ordinary radioactive indicators are not able to capture the hyperactivity of tumor cells [1]

  • Magnetic Resonance Imagery (MRI) and Computed Tomography (CT) scans are regarded as the best diagnostic tracers to capture disruption in BBB

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Summary

Introduction

The brain is considered one of the most important organs, being responsible for memory, emotions, vision, motor skills, reactions, respiration, and a lot of other regulating functions of the human body. These functions are severely affected if some tumor starts growing inside the brain. As the brain is filled with the blood-brain barrier (BBB), so the ordinary radioactive indicators are not able to capture the hyperactivity of tumor cells [1]. Magnetic Resonance Imagery (MRI) and Computed Tomography (CT) scans are regarded as the best diagnostic tracers to capture disruption in BBB

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