Abstract
Point mutation and complementary theory are two controversial mechanisms of tRNA evolution. To identify the predominant or most suitable mechanism to explain modern tRNA evolution, this paper presents a rough evolution model for modern tRNA sequences using computer simulation. The tRNA networks of the sequences produced by the model were compared with the real tRNA network. It was found that when the ‘ancestor sequences’ have a probability greater than 50% of mutating by the point mutation mechanism and a probability less than 50% of mutating by the complementary anticodon method at the same time, the tRNAs produced by the model should have a network behavior similar to that of the real tRNAs network.
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