Abstract
The cell kinetics of lymphoid tissue from the germinal centre of the BALB/c mouse spleen have been studied using3H-TdR and stathmokinetic techniques employing vincristine sulphate. FLM data were analysed using a computer program which yielded a cell cycle time of 13.03 h. Prednisolone produced a fall in the cell birth rate, mitotic index and labelling index (P < 0.02), prolonging apparent cell cycle time by 7.87 h. Splenic weight also fell significantly in the Prednisolone treated group (P< 0.001).
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Schedule a callMore From: Virchows Archiv. B, Cell pathology including molecular pathology
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