Abstract
The basal forebrain complex (BFC) is a small but intricate structure. Its organization and function is hard to investigate using conventional methods, especially in humans. By combining new methods of research we present a comprehensive overview of this complex, in order to better understand its function in normal and diseased brains.MethodsThe right and left BFC of a 29-year-old male were reconstructed from gallcocyanin (Nissl) stained 440 µm-thick serial horizontal sections by using advanced computer-assisted 3D reconstruction software.ResultsThe reconstructed components in the present case include Ch2, Ch3, Ch4am-al, Ch4i, Ch4p, juxtacommissural, Ayala’s medial (subpallidal) and lateral (periputaminal) subnuclei. These components are arranged in an arch-like course mainly beneath the anterior commissure. The bilateral volume of all subnuclei was 99.06 mm3, the left side accounting for 48.05 mm3. Some of the subnuclei exhibited volume asymmetry indices varying from 28.3 to 12.9%.The volume of Ayalas’ lateral or periputaminal nucleus was 9.7% higher on the right, than on the left side.ConclusionsOur methodological approach promises to be highly efficient and reproducible in studying morphofunctional correlations in complex cognitive features
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
