Computer aided designing and finite element analysis for development of porous 3D tissue scaffold - a review

Abstract

Biodegradable porous tissue scaffolds plays a crucial role in development of tissue/organ and development of these biomimetic porous tissue scaffold with accurate porosity could be achieved with the help of latest analysis techniques known as computer aided tissue engineering (CATE) which consists of computer tomography (CT) scan, magnetic resonance imagining (MRI), functional magnetic resonance imagining (FMRI), computer aided designing (CAD), finite element method (FEM) and other modern design and manufacturing technologies for development of 3D architecture of porous tissue scaffolds can be fabricated with reproducible accuracy in pore size. The aim of this paper is to review and elaborate the various recent methods developed in computer aided designing, finite element analysis and solid freeform fabrication (SFF) for development of porous three dimensional tissue scaffolds.