Abstract

Introduction:Fibrous dysplasia (FD) is a fibroosseous lesion of the osseous structures of the body. It is not a commonly reported lesion yet it is considered as an important lesion which can affect the maxillofacial region as well. As a result, it can cause deformity of the jaw bones which can further lead to severe facial asymmetry. Craniofacial fibrous dysplasia (CFD) is one of the subtypes of FD that can affect the bones of the craniofacial complex, including the mandible and maxilla. It can also present as facial asymmetry and can be investigated with the help of Maxillofacial Radiology and Imaging. The radiographic findings may vary according to the extent and degree of the disease. Although conventional radiographs provide a good clue regarding the lesion, advanced maxillofacial imaging is capable of providing detailed extent of the disease. Furthermore the classification of CFD is not very clear in the literature.Case Report:This particular paper attempts to document and report the CT appearance of CFD with an attempt to propose a better classification system for the same. Four different patients are reported which presented with FD with involvement of bones of craniofacial region. Working diagnosis of CFD was made with the help of clinical features as well as with radiographic assessment. Advanced imaging included CT scan of the lesions. The article highlights the importance of computed tomography in diagnosis as well as assessment of extent of the disease.Conclusion:It can be concluded that the Dental professionals must be aware regarding the different radiographic appearances of CFD. Advanced imaging modality like CT can provide with exact diagnosis as well as extent of the lesions like FD. Further collaboration of researchers is required to incorporate this proposed change in classification of CFD.

Highlights

  • Fibrous dysplasia (FD) is a fibroosseous lesion of the osseous structures of the body

  • Researchers have revealed its association with mutation in the gene (GNAS I) [21 - 24] which results in the encoding of the subunit of stimulatory G-protein (Gs) [21 - 24]. This will eventually results in the proliferation and differentiation of preosteoblasts due to increased production of cyclic adenosine monophosphate [2, 4 - 9, 21 - 24]

  • Craniofacial fibrous dysplasia (CFD) is another type of FD which was identified by Daves and Yardley with the involvement of two or more facial and cranial bones [21, 23, 46]

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Summary

Conclusion

It can be concluded that the Dental professionals must be aware regarding the different radiographic appearances of CFD. Advanced imaging modality like CT can provide with exact diagnosis as well as extent of the lesions like FD. Further collaboration of researchers is required to incorporate this proposed change in classification of CFD. Keywords: Classification update, Computed tomography, Craniofacial fibrous dysplasia, Fibrous dysplasia, Ground glass appearance, Panoramic radiographs.

INTRODUCTION
CLINICAL PRESENTATION
DIAGNOSIS
CASE REPORTS
Findings
DISCUSSION
CONCLUSION
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