Abstract
Abstract The purpose of this study was to evaluate the clinical application of computed tomography (CT)-guided (125)I seed implantation for patients who could not undergo or were unwilling to receive repeated surgery, chemotherapy, or radiotherapy for unmanageable cervical lymph node metastases in head and neck cancer (HNC). From February 2010 to December 2013, 31 patients with cervical lymph node metastases in HNC underwent CT-guided (125)I seed implantation. The Karnofsky performance score (KPS), tumor volume, and numeric rating Scale (NRS) at 3-months and 6-months postimplantation were compared with pre-implantation, and local control rate (LCR), overall survival rate (OSR), and complications at 1 and 2 years were assessed . The tumor volume was significantly reduced at 3- and , 6-month postimplantation (21.23 ± 8.83 cm(2) versus 9.19 ± 7.52 cm(2); 21.23 ± 8.83 cm(2) versus 6.42 ± 9.79 cm(2); P
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