Abstract

BackgroundMortality after out-of-hospital cardiac arrest (OHCA) with return of spontaneous circulation (ROSC) remains high despite numerous efforts to improve outcome. For patients with suspected coronary cause of arrest, coronary angiography is crucial. However, there are other causes and potentially life-threatening injuries related to cardiopulmonary resuscitation (CPR), which can be detected by routine computed tomography (CT).Materials and MethodsAt Hannover Medical School, rapid coronary angiography and CT are performed in successfully resuscitated OHCA patients as a standard of care prior to admission to intensive care. We analyzed all patients who received CT following OHCA with ROSC over a three-year period.ResultsThere were 225 consecutive patients with return of spontaneous circulation following out-of-hospital cardiac arrest. Mean age was 64 ± 13 years, 75% were male. Of them, 174 (77%) had witnessed arrest, 145 (64%) received bystander CPR, and 123 (55%) had a primary shockable rhythm. Mean time to ROSC was 24 ± 20 min. There were no significant differences in CT pathologies in patients with or without ST-segment elevations in the initial ECG. Critical CT findings qualifying as a potential cause for cardiac arrest were intracranial bleeding (N = 6), aortic dissection (N = 5), pulmonary embolism (N = 17), pericardial tamponade (N = 3), and tension pneumothorax (N = 11). Other pathologies were regarded as consequences of CPR and relevant for further treatment: aspiration (N = 62), rib fractures (N = 161), sternal fractures (N = 50), spinal fractures (N = 11), hepatic bleeding (N = 12), and intra-abdominal air (N = 3).ConclusionEarly CT fallowing OHCA uncovers a high number of causes and consequences of OHCA and CPR. Those are relevant for post-arrest care and are frequently life-threatening, suggesting that CT can contribute to improving prognosis following OHCA.

Highlights

  • Out-of-hospital cardiac arrest (OHCA) remains a striking challenge for emergency and intensive care medicine, and constitutes one of the main causes of in-hospital mortality worldwide [1]

  • Results from Coronary Angiography after Cardiac Arrest without ST-Segment Elevation (COACT) and Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation (TOMAHAWK) suggest that if no ST-segment elevation is present, delayed coronary angiography has no disadvantage for patients [21, 22]

  • As supported by the trial results from COACT and TOMAHAWK and the real-world experience from Hannover Cooling Registry (HACORE), we do believe that a computed tomography (CT) scan as initial diagnostic test should be favored in all OHCA patients without ST-segment elevations

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Summary

Introduction

Out-of-hospital cardiac arrest (OHCA) remains a striking challenge for emergency and intensive care medicine, and constitutes one of the main causes of in-hospital mortality worldwide [1]. Coronary angiography and percutaneous intervention have emerged as a central part of early in-hospital care following OHCA due to the high prevalence of myocardial infarction as cause of arrest [3, 4, 7]. Urgent coronary angiography is recommended by the European Resuscitation Council (ERC) and European Society of Cardiology guidelines in case of return of spontaneous circulation (ROSC) with STelevation and in resuscitated patients without ST-elevation, if myocardial infarction is assumed [8, 9]. Mortality after out-of-hospital cardiac arrest (OHCA) with return of spontaneous circulation (ROSC) remains high despite numerous efforts to improve outcome. There are other causes and potentially life-threatening injuries related to cardiopulmonary resuscitation (CPR), which can be detected by routine computed tomography (CT)

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