Abstract
In this paper, a computational study was performed to design a compact and high sensitive photonic crystal for the early detection of cancer cells. The plane wave expansion (PWE) and finite-difference time-domain (FDTD) methods were used to determine the dispersion and optical properties of light under variable refractive indices, respectively. The proposed PC-based sensor provided a wide band structure and very-good confinement of light in the sensing area, corresponding to vary sensitive refractive index variations. The effect of lattice constant of PC and radius of the sensing region on the sensitivity of the biosensor were studied. A sensitivity of 15 085 nm/RIU and Q-factor of 81.58 were obtained, ensuing a low detection limit of 0.01 and a high Figure of Merit (FOM) of 159.54 RIU<sup>−1</sup>. Such combinations made an attribute to the proposed structure to perform label-free bio-sensing in cancer cells detection and other points of medical care diagnosis applications.
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