Abstract
Part 1 Introduction: an overview of computing with DNA and protein sequences. Part 2 Sources of information: databanks of protein sequences - the National Biomedical Research Foundation (NBRF) protein sequence database, peptide and protein databanks in Japan, additional protein sequence databanks databanks of nucleic acid sequences - GenBank, the EMBL data library databanks of three-dimensional structures - the protein databank. Part 3 Program systems: computer access to sequence databanks the Protein Identification Resource (PIR) software program systems for minicomputers. Part 4 The technical background: gels to sequences computers in modern science an introduction to computer networks. Part 5 Scientific applications: sequence comparison and alignment - the measurement and interpretation of sequence similarity analysis of DNA sequence data prediction of secondary structure of proteins hydrophobicity profiles molecular evolution conclusion - what shall one do with a newly-determined sequence. Part 6 Prospects: the future of computational molecular biology.
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