Computational model for breast cancer diagnosis using HFSE framework

Abstract

Mammography is one of the imaging modalities used in diagnosing breast cancer at an earlier stage. Misdiagnosis leads to risks for the patients. Better feature extraction and selection techniques can reduce misdiagnoses as they are essential in better-performing classifiers. The proposed approach in this paper introduces a novel Hybrid Feature Extraction and Hybrid Feature Selection (HFSE) framework. It uses mammograms from Digital Database for Screening Mammography (DDSM) datasets to classify mammograms into benign and malignant images. This paper presents a novel hybrid feature extraction approach from the Gray level co-occurrence matrix (GLCM), Linear local binary pattern (LBP), Gabor, and Tamura. Combinedly, it extracts 104 features to train the advanced classifiers such as Logistic Regression, Linear Perceptron, Support Vector Machine, Decision Tree, and Artificial Neural Network. The proposed Hybrid feature extraction method vigorously compares combinations of existing single feature extraction methods. The paper also presents a novel hybrid feature selection approach to choose a subset of the most relevant feature. It compares the Intrinsic feature with the proposed hybrid feature selection method. Hyperparameter tuning and Pipeline optimization techniques applied to the classifiers improve their performance metrics. The experimental results show that the proposed framework performs better using Hybrid feature extraction and feature selection on Artificial Neural Networks. This paper makes a comparative analysis of the related works. It outperforms by achieving a classifier accuracy of 94.57%, specificity of 91.80%, the sensitivity of 95.59 %, and an F1-score of 94.89% on Artificial Neural Networks.