Computational analysis on oxidoreductase of sulfate reducing bacteria: Towards understanding biofilm-metal interaction

Abstract

The deterioration of metal due to microbial activity is termed biocorrosion or microbially influenced corrosion (MIC). Owing to its economic and environmental importance, MIC has been the subject of extensive studies for the past five decades Sulfate-reducing bacteria (SRB) is one of the agent that colonize metal surface and cause localized corrosion. The present study was carried out to gain an insight into biochemical aspect of oxidoreductase of sulfate-reducing bacteria (SRB) which is possibly responsible for MIC. A computational approach was employed to obtain informations of protein domain architecture, biological processes, subcellular locations, physicochemical properties and protein-protein interaction network. By using as series of online publicly available bioinformatics tools, our comprehensve data has increased our understanding of mechanisms governing MIC by SRB. We suggest that, the deterioration of metal may be contributed by the electron flow from metal surface to metal ion-binding domains of SRB oxidoreductase. The acquired electrons are utilized by SRB to support energy production and its colonization on metal surface The participation of SRB oxidoreductase in high number of protein-protein interaction also may be important for establishment of SRB biofilm on metal surface The discovery of these informations are very useful for further wet lab approach to characterize the biofilm-metal surface interaction.