Abstract

Abstract A computer program (“PROSEQ2”) was designed for determining the amino acid sequence of polypeptides from molecular weights and N-terminal amino acid residues of two or more sets of peptide mixtures obtained from polypeptides by two or more specific cleavage methods, together with 3-phenyl-2-thiohydantoin derivatives of amino acids released from two or more sets of peptide mixtures by Edman-degradation. Computation of sequences of several polypeptides using this program is described.

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