Abstract
Nasopharyngeal carcinoma (NPC) is a distinct head and neck tumour associated with Epstein Barr virus infection. This case report describes a 60-year-old woman with a history of NPC who developed after an initial treatment, extensive skull base and intracranial invasion, causing compression of the brainstem and cerebellum, and cranial nerve palsies. Intracranial invasion is a prognostic factor indicating advanced disease, however direct compression of the brainstem by the tumour is not a frequent occurring.
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