Abstract
IntroductionPrognostic situations differ in patients with malignant intracranial tumors. We focused on the quality of life, ability of daily living, and cognitive function of patients in the perisurgery period and investigated the correlation between them and the prognosis of patients.Materials and MethodsPatients with malignant intracranial tumors admitted to Peking Union Medical College Hospital from May 2018 to August 2020 for surgery were included. The evaluations were performed 6 times in the perisurgery period. The questionnaires for assessment included QLQ‐C30, ADL, and so forth.ResultsA total of 165 patients were included (115 glioma and 50 brain metastases). Patients had their worst performance at the 7‐day postsurgical assessment (EORTC QLQ‐C30, ADL, HAD‐D, Frail Scale, MMSE, MoCA, CSHA‐FI, and NANO) and recovered at the 1‐month postsurgical assessment (p < .05). Patients with left‐sided tumors had significantly worse cognitive function than patients with right‐sided tumors before surgery and at 7 days, 1 month, and 6 months after surgery (p < .05). The scores of QLQ‐C30 and QLQ‐BN20 at 1 month, 3 months, 6 months, and 1 year after surgery were used to reflect the prognosis, and the preoperative MoCA, NANO, CCI, CSHA‐FI, and HAD score might predict the quality of life and nutrition status after operation.ConclusionThe quality of life and daily living ability of patients with malignant intracranial tumors decreased significantly 7 days after the surgery but recovered 1 month after the surgery. Patients with left hemisphere lesions had a worse cognitive function, while the ADL is associated with short‐term prognosis. The comprehensive evaluation of the perisurgical period can indicate the prognosis of patients and further guide clinical decision‐making.
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