Abstract
AbstractWe report a hitherto undescribed interaction of a deletional (δβ)°‐thalassemia and a deletional hereditary persistence of fetal hemoglobin (HPFH) in an adult Thai individual. He was a 40‐year‐old Thai male who had the following hematologic data: Hb 13.9 g/dL, Hct 43.8%, MCV 78.0 fL, MCH 24.7 pg, MCHC 31.6 g/dL, and RDW 17.1%. Hemoglobin analysis revealed 97% Hb F with Gγ‐globin chain predominant. Globin gene analyses demonstrated that he carried the GγAγ(δβ)°‐thalassemia deletion in trans to the HPFH‐6. Hematologic data of the patient were compared to those of the heterozygotes for these high‐Hb F determinants found in his parents and an unrelated Thai patient with a compound HPFH‐6/deletion–inversion Gγ(Aγδβ)°‐thalassemia previously described. Am. J. Hematol. 80:119–123, 2005. © 2005 Wiley‐Liss, Inc.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
