Abstract
Cryptococcus neoformans is a predominantly saprophytic yeast that can cause serious infections, mostly in individuals with acquired immunodeficiency syndrome (AIDS). A prominent virulence factor of Cryptococcus neoformans is its capsule. This is constituted mainly of glucans; the capsular polysaccharide, glucuronoxylomannan (GXM) (composed of mannose, xylose, glucuronic acid), and at least two minor carbohydrate antigens, galactoxylomannan (GalXM) and mannoproteins (MP).
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