Abstract
Ginseng a plant widely used in phytomedicine due to its pronounced biological activity, primarily connected with the high content of saponins (ginsenosides). The cultivation of ginseng in the Altai Republic is currently being resumed. The production of phytopreparations requires an assessment of the quality of raw plants. There is a lack of information on the compostion and medicinal properties of ginseng grown in the Altai Republic.In this research, for the first time, an analysis of Altai Ginseng roots was carried out by HPLC-QOT MS. The profile of the main biologically active substances — ginsenosides — was determined and compared with that of the Chinese analogue. We found that Altai ginseng contains 17 ginsenosides, 12 of which are recommended for the detection by NIST. The content of 7 main ginsenzides (Rb1, Rc, Re, Rb2, Rg1, Rg, Rd) ranges from 680 to 5,375 μg/g of raw material. The ginsenzide profiles of ginseng plants grown in Altai and China were found to be similar.It is shown that ginseng roots contain a rich composition of ginsenosides, which are present in high concentrations. Consequently, this raw material has a significant potential for the manufacture of extracts for their further use in phytopreparations for preventive medicine in Russia and other countries.
Highlights
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia 143442, Russian Federation, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1
Ginseng a plant widely used in phytomedicine due to its pronounced biological activity, primarily connected with the high content of saponins
There is a lack of information on the compostion and medicinal properties of ginseng grown in the Altai Republic
Summary
Scientific Center of Biomedical Technologies of the Federal Medical and Biological Agency of Russia 143442, Russian Federation, Moscow Region, Krasnogorsk District, Svetlye Gory Village, 1. Нестеров «Идентификация компонентного состава женьшеня, культивируемого в Республике Алтай». It is shown that ginseng roots contain a rich composition of ginsenosides, which are present in high concentrations. This raw material has a significant potential for the manufacture of extracts for their further use in phytopreparations for preventive medicine in Russia and other countries. Введение В России и во всём мире ежегодно увеличивается потребление лекарств, фитопрепаратов, БАД, природной косметики на основе растений и, соответственно, растёт потребность в получении сырья для их изготовления. Основным классом БАВ женьшеня являются тритерпеновые гликозиды (гинсенозиды). В настоящее время состав женьшеня, культивируемого в Республике Алтай, в частности, его гинсенозидный профиль, другие БАВ — не исследованы.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
