Composition ratio of laryngopharyngeal reflux disease in outpatients and evaluation of diagnostic accuracy by physicians

Abstract

Objective To investigate the diagnosis consistency of laryngopharyngeal reflux disease(LPRD) between doctors and the evaluation of reflux symptom index(RSI) scale, and explore its influencing factors among outpatients of otolaryngology, head and neck surgery department. Methods From July 2017 to June 2018, 2 066 adult patients(1 320 males and 746 females), age(39.0±11.7) years old, ranging from 18 to 84 years old, were randomly selected by isometric random sampling method.Patients under the guidance of medical staff to fill in questionnaires, including social demographic characteristics, smoking, drinking alcohol, using acid suppression, stomach, such as dynamic drug treatment based on RSI score, understanding of patients with reflux sex composition of strep throat, assessment was diagnosed results consistent with the gold standard and its influencing factors. Results Based on the RSI scale, the composition ratio of laryngopharyngeal reflux disease was 12.20%(252/2 066). The sensitivity, specificity, positive predictive value, negative predictive value, youden index and Kappa value were 23.02%, 98.46%, 67.44%, 90.20%, 21.47% and 0.30, respectively, indicating a low consistency.Compared with other subgroups, the results of RSI scale in 35 to 45 years old group, male group, smoking group, drinking group, using acid-inhibiting group and gastric dynamic group were consistent with the results of physicians′diagnosis. Conclusion The consistency between the evaluation results of LPRD diagnosed by physicians and the RSI scale is low, and the effective use of the RSI scale in the diagnosis of laryngopharyngeal reflux disease is helpful to improve the early treatment and intervention of LPRD patients. Key words: Laryngopharyngeal reflux disease; Reflux symptom index; Composition ratio; Diagnostic consistency