Abstract

Recently a nephrotic syndrome, characterized by proteinuria, hypoalbuminemia, hypercholesterolemia, hyperlipemia, and edema, has been produced in rats by the subcutaneous injection of an aminonucleoside (6 dimethylamino purine, 3-amino-d-ribose). The serum changes in nephrosis may be reflexed in lymph and tissue fluid. Information on the composition of lymph in nephrosis is, however, limited. The present studies were carried out to evaluate the role of lymph in carrying various components in renal or nephrotic edema to the general circulation.

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