Abstract
Composites of amorphous carbonated apatite and poly-(R)-3-hydroxybutyrate (PHB) and poly-(R)-3-hydroxybutyrate-co-(R)-3-hydroxyvalerate (PHBHV), respectively, were studied by pH monitoring upon immersion in water and by long-term osteoblast culture. For comparison, α-tricalcium phosphate (α-TCP), one glass ceramic (GB 9N), and one bioglass (Mg 5) were subjected to the same experiments. Excellent cell proliferation was found on the composite of calcium phosphate with PHB and on the reference materials (α-TCP, glass ceramic, bioglass). In contrast, cell death was observed repeatedly on the composite with PHBHV. A composite of amorphous calcium phosphate and PHB appears to be well suited as slowly biodegradable bone substitution material.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
