Abstract
Composite tumor of larynx, a recently included entity in the current WHO classification, is often a difficult pathological diagnosis, especially in small biopsies. We report a case of laryngeal composite tumor, initially misdiagnosed as squamous cell carcinoma, which later turned out to be composite in nature, with associated neuroendocrine (small cell carcinoma) component. This report emphasizes the need for obtaining deeper biopsies and their thorough pathological examination to improve the diagnostic accuracy. Keywords: combined small cell carcinoma; composite tumor; larynx; small cell carcinoma; squamous cell carcinoma.
Highlights
CC CC BYMadhu Rajeshwari,[1] Pirabu Sakthivel,[2] Rijendra Yogal,[2] Smriti Panda,[2] Chirom Amit Singh,[2] Deepali Jain,[1]
Neuroendocrine tumors (NET) of the larynx account for less than 0.5% of all laryngeal tumors, the most common being atypical carcinoid followed by small cell carcinoma.[3]
We report a case of combined small cell carcinoma which was initially diagnosed as primary SCC of the larynx and had an initial complete response
Summary
Madhu Rajeshwari,[1] Pirabu Sakthivel,[2] Rijendra Yogal,[2] Smriti Panda,[2] Chirom Amit Singh,[2] Deepali Jain,[1]
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