Composite Nonwovens Based on Carboxymethyl Cellulose for Wound Dressing Materials

Abstract

Composite nonwovens were prepared by the lamination of polypropylene spunbond nonwoven with carboxymethyl cellulose/hollow viscose rayon blend nonwoven and their various properties, such as liquid handling properties, wet tensile strength, moisture evaporation rate, and in-vitro cytotoxicity, were evaluated for moist wound dressing applications. Fluid retention capacity, wet dimensional stability, and wet tensile strength of carboxymethyl cellulose/hollow viscose rayon nonwoven were significantly improved by the lamination with polypropylene spunbond nonwoven. The polypropylene spunbond nonwoven layer did not affect the liquid spreadability and moisture evaporation. The composite nonwoven was not cytotoxic. Considering liquid handling properties and wet properties, composite nonwoven, in which polypropylene spunbond nonwoven on both sides of carboxymehtyl cellulose/hollow viscose rayon nonwoven, was found to be the most desirable wound dressing material of those assessed in this study.