Abstract

The simultaneous occurrence of thymoma and peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) has not been previously reported, to our knowledge. We describe a 59-year-old ethnic Filipina woman with myasthenia gravis who was found to harbor an invasive lymphocyte-rich thymoma (World Health Organization [WHO] type B1). Subsequent pathologic examination of her mediastinal and abdominal lymph nodes revealed concurrent PTCL-NOS. A bone marrow examination revealed T-cell lymphoma, which was confirmed by flow cytometric and T-cell receptor gene rearrangement analysis. * NHL : non-Hodgkin lymphoma WBC : white blood cell PTCL-NOS : peripheral T-cell lymphoma not otherwise specified MRI : magnetic resonance imaging CT : computed tomographic WHO : World Health Organization HTLV-1 : human T-cell leukemia virus type 1 HTLV-2 : human T-cell leukemia virus type 2 PCR : polymerase chain reaction TCR : T-cell receptor CML : chronic myelogenous leukemia

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