Abstract
Children with occult pneumococcal bacteremia have not been considered to be at significant risk of developing complications. However, three of seven children, without an apparent source of pneumococcal bactermia, developed meningitis after a period of well-being, and two others developed an identifiable respiratory focus of infection. Meningitis occurred in spite of oral or low-dose intravenous penicillin therapy. We conclude that the identification of occult pneumococcal bacteremia places the child at significant risk to develop serious sequelae and that initiation of high-dose parenteral penicillin therapy, as in the treatment of pneumococcal meningitis, is indicated.
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