Abstract
Epidermolysis bullosa acquisita (EBA) is a rare kind of autoimmune blistering disease associated with autoimmunity to type Ⅶ collagen, which is the major component of anchoring fibrils at the dermal-epidermal junction. EBA may involve the mucous membrane and skin, and mainly manifests as diverse subepidermal blisters leaving milia and atrophic scars after healing. Recently, it has been described in association with a number of other skin and systemic diseases, including gastrointestinal diseases, autoimmune diseases, endocrine diseases, infectious diseases, hematological diseases and neoplastic diseases. Some of the complications were described in case reports, and some were investigated about the relevant pathogenesis. Key words: Epidermolysis bullosa acquisita; Immune system diseases; Hematologic diseases; Carcinoma; Skin diseases
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