Complications, Complete Examination Rate and Gastrointestinal Transit Time of OMOM Capsule Endoscopy: An Analysis with 1,068 Cases

Abstract

Background and Objective: A new wireless OMOM capsule endoscope (OMOM CE), developed by Jianshan Science & Technology (Group) Co., Ltd, Chongqing, China, has been widely used in China and in some areas of Southeast Asian and European countries. About 53,000 OMOM capsules have been ingested since 2004. However, there are few published studies that summarize OMOM capsule endoscopy on complications, complete examination small bowel rate (CER), gastric transit time (GTT), and small bowel transit time (SBTT) with large sample. Methods: A database was retrieved from the Jianshan Science & Technology Ltd. OMOM CE Database. The 1,068 cases were from 17 endoscopy centers that used the OMOM CE system in Mainland China. The complications, complete small bowel examination rate (CER), gastric transit time (GTT), small bowel transit time (SBTT), and total work time were recorded and analyzed. Results: The major complication of OMOM CE was capsule retention, which were seen in 23 patients (esophageal 4, gastric 9, afferent loop 1, small bowel retention 9). The overall retention rate was 2.15%. Four capsules retained in the small bowel were surgically removed, and the remainders were successfully removed by gastroscopy or double balloon enteroscopy. The overall CER of OMOM CE was 82.68%. In the 185 patients with uncompleted examination, the delayed gastric emptying was the major cause (68 patients' GTT >120 min, 36.8%). The CER was not related to the gender or age. The decrease in CER was positively related to the increase in GTT, and inversely related to the increase in total work time (TWT) of OMOM CE (Both p < 0.001). The CER in the non-OGIB group was greater than OGIB group (78.5% vs. 86.5% p < 0.001). The mean GTT, SBTT and TWT were 68 min (rang 1∼543 min), 261 min (rang 27∼690 min), and 468 min (rang 168∼911 min), respectively. Conclusions: This is the first large report on OMOM capsule endoscopy, and the capsule retention rate is very low and comparable with that of Given PillCam capsule system. The complete small bowel examination rate was 82.6%, which was related to gastric transit time and total work time of OMOM capsule, but not related to gender and age.