Complications and risk factors of neuroendoscopic treatment of intraventricular tumors

Abstract

Objective To investigate the complications and risk factors of endoscopic treatment of intraventricular tumors. Methods A total of 82 cases of intraventricular tumors were enrolled into this study who underwent neuroendoscopic treatment at Neurosurgery Department, Beijing Tiantan Hospital, Capital Medical University from February 2004 to July 2016. All patients received complete follow-up lasting for over 2 years and their postoperative complications were documented. We analyzed the risk factors related to the patients＇ complications. Results All 82 patients underwent successful operations. There was no death. Total or subtotal resection was achieved in 64 (78.1%) patients, partial resection in 10 (12.2%) and tumor biopsy in 8 (9.7%). Postoperative complications occurred in 25 (30.5%) patients and included intracranial infection in 17 (20.7%), postoperative intraventricular hemorrhage in 5 (6.1%), subcu-taneous effusion in 2 (2.4%) and neurological impairment in 1 (1.2%). Recurrence was reported in 10 (13.5%) cases 2 years post operation among 74 patients who underwent resection. Logistic regression analysis showed that preoperative hydrocephalus (OR=24.055, 95%CI: 2.910-198.813, P=0.003), hard tumors (OR=28.975, 95%CI: 2.894-290.091, P=0.004) and blood vessel-rich tumors (OR=43.118, 95%CI: 2.134-871.302, P=0.014) were independent risk factors of postoperative complications. Conclusions Neuroendoscopic resection of intraventricular tumors is safe and effective. Intracranial infection seems to be the major complication. Preoperative hydrocephalus, hard tumors and blood vessel-rich tumors are independent risk factors for endoscopic treatment of intraventricular tumors. Key words: Natural orifice endoscopic surgery; Cerebral ventricle neoplasms; Postoperative complications; Risk factors