Complications and Outcome of Patients of Pre-eclampsia and Eclampsia Presenting to Medical Wards of Mayo Hospital Lahore

Abstract

Aims and Objectives: To find out the complications and outcome of patients of pre-eclampsia and eclampsia presenting to medical wards of mayo hospital Lahore. Material and Methods: This study was carried out from June 2007 to June 2008 on patients presenting to medical wards of Mayo Hospital Lahore with history of pre-eclampsia and eclampsia. Study Design: It is a retrospective type of study. Results: Out of 100 patients presenting to medical wards, 60 were primigravida and 40 multigravida. The age of the patients was between 18 - 40 years. 35 patients reported after delivery out of which 20 had spontaneous vaginal delivery and 15 had C-section, remaining 65 were pregnant at presentation. Out of 100 patients 33 developed CNS complications in which 26 developed seizures, 3 developed cerebral hemorrhage, 1 developed cerebral infarction, 2 reported with severe headache and 1 developed blurred vision. 30 patients developed acute renal failure. 25 patients had HELLP syndrome, 6 had disseminated intravascular coagulation, 4 had abruptio placentae and 2 developed ARDS. Out of 100 patients 47 patients were discharged, 24 patients died and 29 patients left against medical advice. Conclusion: Pre-eclampsia and eclampsia are associated with increase in maternal and perinatal morbidity and mortality. The importance lies in the diagnosis direct input by the clinician and special expertise in management so that maternal and perinatal morbidity can be brought down with early reference to tertiary care level hospitals. Key Words: Pre-eclampsia, Eclampsia, Hypertension, Seizure, HELLP syndrome.