Abstract

Introduction: Diabetes is a disease with a high prevalence and macrovascular complications of diabetes are among the most feared consequences of diabetes, with high costs. Constant evolution of knowledge in this area justifies a new review of the literature on this topic. Objectives: To define the goals of primary and secondary prevention of macrovascular complications in diabetic patients, based on the best available scientific knowledge. Methods: A review of guidelines, recommendations, randomized controlled trials and meta-analyses of prevention of macrovascular complications of diabetes was performed. Results: In diabetic patients it is necessary to manage all risk factors of vascular disease. For primary prevention, lifestyle modifications are of great importance. Diet should be modified to reduce fat, salt and caloric intake, and regular exercise should be promoted. Smokers should be encouraged to quit. Glycemic levels should be controlled to achieve a HbA1C

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