Abstract

Background and question Colchicine is the gold standard treatment for prevention of inflammatory attacks and prevention of reactive amyloidosis in FMF. However, noncompliance to colchicine treatment is common among FMF patients. On the other hand, the disease may not be controlled in some patients despite use of full dose colchicine. In this study, we aimed to investigate the rates of disease control, compliance to colchicine treatment, and need for an additional treatment despite use of full dose colchicine in patients with FMF in Corum region where FMF is common in Turkey.

Highlights

  • Background and questionColchicine is the gold standard treatment for prevention of inflammatory attacks and prevention of reactive amyloidosis in Familial Mediterranean Fever (FMF)

  • Noncompliance to colchicine treatment is common among FMF patients

  • We aimed to investigate the rates of disease control, compliance to colchicine treatment, and need for an additional treatment despite use of full dose colchicine in patients with FMF in Çorum region where FMF is common in Turkey

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Summary

Introduction

Colchicine is the gold standard treatment for prevention of inflammatory attacks and prevention of reactive amyloidosis in FMF. Noncompliance to colchicine treatment is common among FMF patients. The disease may not be controlled in some patients despite use of full dose colchicine. We aimed to investigate the rates of disease control, compliance to colchicine treatment, and need for an additional treatment despite use of full dose colchicine in patients with FMF in Çorum region where FMF is common in Turkey

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