Abstract

BackgroundCobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions. There are, however, no reliable data about the characteristics of unfolding and visibility of this stent alloy in vivo. The aim of this study is to compare cobalt chromium coronary stents with conventional stainless steel stents using intracoronary ultrasound.MethodsTwenty de novo native coronary stenoses ≤ 20 mm in length (target vessel reference diameter ≥ 2.5 and ≤ 4.0 mm) received under sequential intracoronary ultrasound either a cobalt chromium stent (Multi-Link Vision®; n = 10) or a stainless steel stent (Multi-Link Zeta®; n = 10).ResultsFor optimal unfolding, the cobalt chromium stent requires a higher balloon deployment pressure (13.90 ± 2.03 atm) than the stainless steel stent (11.50 ± 2.12 atm). Furthermore, the achieved target vessel diameter of the cobalt chromium stent (Visibility-Index QCA/IVUS Multi-Link Vision®1.13 / Multi-Link Zeta® 1.04) is more easily overrated by Quantitative Coronary Analysis.ConclusionThese data indicate that stent material-specific recommendations for optimal implantation pressure and different stent material with an equal design should both be considered in interpreting QCA-analysis.

Highlights

  • Cobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions

  • These data indicate that stent material-specific recommendations for optimal implantation pressure and different stent material with an equal design should both be considered in interpreting QCA-analysis

  • We investigated the balloon deployment pressure-related behaviour of a cobalt chromium stent (Multi-Link Vision®), comparing it to a designed conventional stainless steel stent (Multi-Link Zeta®) using intravascular ultrasound

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Summary

Introduction

Cobalt chromium coronary stents are increasingly being used in percutaneous coronary interventions. The aim of this study is to compare cobalt chromium coronary stents with conventional stainless steel stents using intracoronary ultrasound. With the addition of coronary stents to percutaneous coronary intervention (PCI), the incidence of re-stenosis has been significantly reduced. Cobalt chromium represents a more biocompatible material that is being increasingly used in coronary stents (Guidant Multi-Link Vision®/Guidant Corporation, Driver-Stent®/Medtronic, Costar-Stent®/Biotronic). In comparison with stainless steel, cobalt chromium has a higher radial strength and radiopacity for similar electronegativity. This allows for the production of thinner struts with a similar radiological visibility[3]

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