Complexing properties of nucleic-acid constituents adenine and guanine complexes

Abstract

Cobalt, nickel and copper complexes of adenine and guanine, as nucleic-acid constituents, were prepared. The adenine and guanine complexes are of tetrahedral and octahedral geometries, respectively. All are of high spin nature. The nickel complexes are of 2:1 metal:ligand ratio with Ni⋯Ni direct interaction in the guanine complex. The coordination bonds of adenine metal complexes are calculated and follow the order: Cu II-adenine<Ni II-adenine<Co I-adenine. The Cu II-adenine complex is the stronger following the softness of the copper, while that of guanine is less covalent. The copper complexes are with stronger axial field. The differential thermal analysis (DTA) and TGA of the complexes pointed to their stability. The mechanism of the thermal decomposition is detected. The thermodynamic parameters of the dissociation steps are evaluated. The complexes are of semi-conducting behaviour for their technical applications. Empirical equations are deduced between the electrical conducting and the energy of activation of the complexes.