Abstract

The aerial parts of the Chinese medicinal plant Hypericum sampsonii yielded two novel metabolites, sampsoniones A and B, which are characterised by their unique tetracyclo-polyketonic core with benzoyl, 3-methyl-2-butenyl and geranyl substituents. Their structures were determined by detailed spectral analysis. Sampsonione A exhibited moderate cytoxicity to P388 cancer cell line.

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