Abstract

Introduction Primary effusion lymphoma (PEL) is a rare malignancy that accounts for 5% of HIV-related non-Hodgkin lymphoma (NHL). It usually presents as a lymphomatous growth in liquid phase within various body cavities such as the pleural, pericardial, and peritoneal spaces. Although extracavitary tumors can occur in PEL, they do so rarely but may be histologically indistinguishable from PEL. PEL s also defined by the expression of Kaposi sarcoma–associated heresvirus (KSHV) (also known as human herpesvirus 8 [HHV8]) in

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