Abstract
Burkitt lymphoma (BL) is a type of non-Hodgkin lymphoma that originates from the malignant transformation of B lymphocytes. A 5-year-old boy presented bilateral swelling between the middle and lower third of the face, with limitation of mouth opening and headache. The computed tomography revealed areas suggestive of a tumor with invasion of the maxillary sinuses and initially of the orbital cavities. Under general anesthesia, an intraoral incisional biopsy was performed. Microscopic analysis revealed atypical lymphoid proliferation, and the immunohistochemical labeling was positive for CD10, CD20, and BCL-6 and in 100% for Ki-67 and negative for BCL-2. The final diagnosis of BL was established. The patient underwent treatment at a referral hospital following the protocol of the Brazilian Society of Pediatric Oncology and remains free of the disease for 24 months. BL is highly aggressive, and the dentist plays an important role in early diagnosis. Acknowledgments: CNPq.
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