Complete remission after radiotherapy in a patient with basaloid squamous cell cancer of the nasal cavity and maxillary sinus – case report and review of literature

Abstract

<b>Aim:</b> The aim of our study is to describe the case of a patient suffering from squamous cell carcinoma of the basaloid nasal cavity, who achieved complete recurrence remission after palliative radiotherapy. </br></br> <b> Case report:</b> We present a clinical case of a patient suffering from basaloid squamous cell carcinoma of the nasal cavity who achie-ved a complete remission of local recurrence following a palliative radiotherapy. In November 2011 the patient underwent a radical, block resection of the tumor withing the nasal cavity and right paranasal sinuses, with margin sampling. The recurrence occurred in June 2012. As she did not qualify for rescue therapy, she received 2 courses of radiation, spaced 6 months apart – 20 Gy in 5 fractions each. A complete remission lasting until 2016 was achieved. Progression free survival from the first series of palliative radiotherapy was 45 months. Overall survival since the diagnosis was 69 months (62 months since the recurrence was diagnosed). </br></br> <b>Discussion:</b> We have conducted a literature review regarding therapeutic options and prognosis and compared it with our case. Basaloid squamous cancer is more aggressive than other squamous cancers. Previous case studies and case series descri-be this type of the disease being treated with surgery, radiation or various multimodality protocols including chemoradiation, surgery followed by radiation and others. </br></br> <b>Conclusions:</b> A conclusion was drawn that the best results were reported in studies which based their therapeutic strategy on radiotherapy.