Complete Genome Sequences of Three Leptospira mayottensis Strains from Tenrecs That Are Endemic in the Malagasy Region

Colette Cordonin,Patrick Mavingui,Céline Toty,Pablo Tortosa

doi:10.1128/mra.01188-18

Abstract

Leptospirosis is a zoonosis caused by Leptospira, a diversified genus containing more than 10 pathogenic species. Tenrecs are small terrestrial mammals endemic in the Malagasy region and are known to be reservoirs of the recently described species Leptospira mayottensis. We report the complete genome sequences of three L. mayottensis strains isolated from two tenrec species.

Highlights

Leptospirosis is an environmental infectious disease caused by spirochetal bacteria belonging to the genus Leptospira
Automatic annotation was performed with the NCBI Prokaryotic Genome Annotation Pipeline [13], which revealed that the VS2413, MDI272, and MDI222 genomes are composed of 3,893, 3,917, and 4,136 coding sequences, respectively
Human leptospirosis on Mayotte is peculiar because it is associated with four distinct bacterial species, including L. mayottensis [14], and characterized by a relatively low fatality rate (0.9%) [15]

Summary

Introduction

Leptospirosis is an environmental infectious disease caused by spirochetal bacteria belonging to the genus Leptospira. Genome sizes and structures (see Table 1) are close to those of previously published ones, with comparably low (Յ40%) GC contents, two chromosomes, and, in the case of T. ecaudatus-borne strains, an additional plasmid [12]. Automatic annotation was performed with the NCBI Prokaryotic Genome Annotation Pipeline [13], which revealed that the VS2413, MDI272, and MDI222 genomes are composed of 3,893, 3,917, and 4,136 coding sequences, respectively.

Results

Conclusion