Abstract
Bacillus anthracis, the etiologic agent of anthrax, is susceptible to beta-lactam antibiotics, but few cases of naturally occurring penicillin-resistant strains have been reported. We report the genome sequence of penicillin-resistant strain Bacillus anthracis PCr, isolated from imported bone powder in 1978 in Japan.
Highlights
Bacillus anthracis, the etiologic agent of anthrax, is susceptible to betalactam antibiotics, but few cases of naturally occurring penicillin-resistant strains have been reported
The phylogenetic analysis of strain PCr using in silico canonical single-nucleotide polymorphism typing [10] and core-genome SNP analysis with an analytical pipeline [11] were performed as previously described [4]
The mutation in the PCr strain is likely to be related to its penicillin resistance, and further investigations are warranted
Summary
The etiologic agent of anthrax, is susceptible to betalactam antibiotics, but few cases of naturally occurring penicillin-resistant strains have been reported. The phylogenetic analysis of strain PCr using in silico canonical single-nucleotide polymorphism (canSNP) typing [10] and core-genome SNP analysis with an analytical pipeline [11] were performed as previously described [4].
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